AVAILABLE INFORMATION FOR
(TRAJENTA DUO 2.5MG/1000MG TABLET)

SALT INFORMATION
Linagliptin 2.5 MG + Metformin 1000 MG

LINAGLIPTIN 2.5 MG
Use
Linagliptin is used in the treatment of Diabetes Mellitus Type-2.
Common Side Effect
Hypoglycaemia (low Blood sugar level) in combination with insulin or sulphonylurea, Headache, Nasopharyngitis (swelling of the Nasal passages and the back of the Throat)
Precaution
Stop taking Linagliptin and call your doctor at once if you have a serious side effect such as :
Severe pain in your Upper Stomach spreading to your back, Nausea and Vomiting, loss of Appetite, fast Heart Rate, fever, sore throat, and headache with a severe blistering, peeling, and red skin rash.
Class of Drug - Dipeptidyl Peptidase-4 Inhibitor
Route of Administration - Oral (Tablet)
Bioavailability - {~30%} (Tmax = 1.5 Hours)
Biological Half Life - (~24 Hours)
Excretion - Feces (80%), Urine (5%)

METFORMIN 1000 MG
Use
Metformin is the first-line medication for the treatment of type 2 diabetes. It is also used in the treatment of polycystic ovary syndrome.
Common Side Effect
Includes gastrointestinal irritation, diarrhea, cramps, nausea, vomiting, increased flatulence; metformin is more commonly associated with gastrointestinal side effects than most other antidiabetic drugs.
Precaution
It should not be used in those with significant liver disease or kidney problems.
Class of Drug - Biguanide Class
Route of Administration - Oral
Bioavailability - 50–60%
Biological Half Life - 4-8.7 Hours
Excretion - Urine 90%